The Science of POM Wonderful

For centuries the pomegranate has been the subject of art and legends. We wanted to find out why.

A number of top scientists in their fields, including a Nobel Laureate, have researched areas including antioxidant activity and the cardiovascular system. To date, multiple peer-reviewed studies have been completed and published, while a number of others are still in progress.

To learn more about the studies, please click any of the following areas of research:

Antioxidant Composition

Comparison of Antioxidant Potency of Commonly Consumed Polyphenol-Rich Beverages in the United States
Navindra P. Seeram, Michael Aviram, Yanjun Zhang, Susanne M. Henning, Lydia Feng, Mark Dreher, and David Heber
Journal of Agricultural and Food Chemistry, published online January 26, 2008

Antioxidant Activity of Pomegranate Juice and Its Relationship with Phenolic Composition and Processing
Gil, MI, Tomas-Barberan, FA, Hess-Pierce, B, Holcroft, DM, and Kader, AA
Journal of Agricultural and Food Chemistry 2000, 48: 4581-4589

Bioavailability

Pomegranate Juice and Extracts Provide Similar Levels of Plasma and Urinary Ellagitannin Metabolites in Human Subjects
Seeram, N, Zhang, Y, McKeever, R, Henning, S, Lee, R, Suchard, M, Li, Z, Chen, S, Thames, G, Zerlin, A, Nguyen, M, Wang, D, Dreher, M, Heber, D
Journal of Medicinal Food 2008, 11(2): 390-394

Pomegranate Juice Ellagitannin Metabolites Are Present in Human Plasma and Some Persist in Urine for Up to 48 Hours1,2
Seeram NP, Henning SM, Zhang Y, Suchard M, Li Z, Heber D.
Journal of Nutrition 2006, 136(10):2481-5

Bioavailability of Ellagic Acid in Human Plasma After Consumption of Ellagitannins From Pomegranate (Punica granatum L.) Juice
Seeram N., Lee R., and Heber D.
Clinica Chimica Acta 2004, 348: 63-68

Review Articles

Scientific and Clinical Monograph for Pom Wonderful Pomegranate Juice
McCutcheon A., Udani J., Brown D.
American Botanical Council, 2008, herbalgram.org